I hope you are well! One of our students asked a question.
The question is about Ginger’s discussion of melatonin/light exposure and vit D in a recent webinar. Sorry I didn’t really get the dots connected or bottom line on the mech which helps with inflammation…if serotonin is released to be converted to melatonin in the dark and melatonin up reg pro inflamm cytokines, how is this good for decreasing inflame?…and where does vit d come in?…I think Im misunderstanding or missing a step lol…Ill check out your blog when I get a chance
One answer about the vitamin D question is – there is scientific query into whether or not low vitamin D levels affect obesity through altering the bioavailability of vit. D – meaning does adipose tissue actually “hoard” vitamin D levels, lowering the overall levels considered to be normal (25(OH)D). Further, is vitamin D’s affect on endothelial function also interrelated with levels of inflammation in the body (as adipose tissue creates a chronic low level of inflammation in the bloodstream and is resistant to change, making it harder for folks to lose weight the longer they are overweight/obese).
These questions are not really answerable right now – and vitamin D research is still new. But, the hormonal action of vitamin D is important enough that rehab. pros. should include discussion of the importance of maintaining normal levels with their patients.
On melatonin – modulation of melatonin is the take-home point, as it relates to circadian rhythm. e.g. those who are in critical care don’t get normal light/dark patterns, and they get virtually no natural light, which has been found to disrupt the circadian rhythm, which then affects cortisol levels – wherein neuroendocrine dysregulation begins and the HPA Axis is adversely affected. Next stop – inflammation.
I do hope this helps – and I’m sorry if I wasn’t clear about those points before. Neuroendocrinology is not typically discussed in rehab/PT, but it should be. It’s absolutely critical to address this system for patient outcomes, which is why yoga is such a fantastic modality for your rehab. toolbox.